For the treatment and control of coccidiosis, Toltrazuril is effective against all intestinal stages of susceptible coccidia. To assist in the development of natural immunity to coccidiosis in breeder and layer replacer stock exposed to continuous challenge of virulent strains of coccidia
 
Contraindications
 
Do not use in birds producing eggs for human consumption.
 
Special warnings for each target species
 
As with all anticoccidials, prolonged use may result in the development of resistant strains.
 
Special precautions for use 
 
Special precautions for use in animals
 
Predilution in water at less than 1:1000 will result in the precipitation of the active ingredient. During treatment all water available to the flock must be medicated. Treatment may be by direct application into the header tanks, or using an accurate water proportioning system.
 
Before use, header tanks should be emptied, thoroughly cleaned and then filled with a known volume of clean water before adding the required amount of Baycox 2.5% Solution. The resulting mixture should be stirred. Header tanks should be inspected at regular intervals for the presence of dust, algae formation and sedimentation.
 
Special Precautions to be taken by the Person Administering the Medicinal Product to Animals
 
Baycox is an alkaline solution. Wear synthetic rubber gloves when handling the concentrated product. Wash any splashes from skin or eyes immediately with water. Do not eat, drink or smoke whilst using the product.
 
Adverse reactions (frequency and seriousness)
 
Not known.
 
Use during pregnancy, lactation or lay
 
See section 4.11
 
Interaction with other medicinal products and other forms of interaction Baycox is compatible with antibiotics such as enrofloxacin, ampicillin, tetracycline, tiamulin and tylosin.
 
Amounts to be administered and administration route
 
Baycox is indicated in water medication at the rate of 25 ppm (1 litre Baycox 2.5% Solution per 1000 litres of drinking water). This should be for a continuous period of 48 hours. Alternatively, it can be added at the higher level of 75 ppm (3 litres/1000 litres) for 8 hours per day on 2 successive days. Two days treatment is sufficient for the therapy of an outbreak of clinical coccidiosis, or control of subclinical coccidiosis during the feeding of ionophores.
 
Overdose (symptoms, emergency procedures, antidotes), if necessary
 
A three – five fold overdose is readily tolerated without any symptoms. If the recommended dose is exceeded beyond 3-5 times, there is a decrease in water intake.
 
Withdrawal Period(s)
 
Birds must not be slaughtered for human consumption until 14 days following last treatment. Do not use in birds producing eggs for human consumption.