Tylan soluble powder is for the control of mycoplasma synoviae airsacculitis in chickens and Mycoplasma gallisepticum S6 in chickens and turkeys. Tylan has also proved useful in reducing the level of infection following stress associated with live vaccination of calves, pigs, chickens and turkeys, and aids control of outbreaks of necrotic enteritis in chickens caused by clostridium perfringens. The active ingredient of Tylan is tylosin tartrate. Tylan is a white to medium yellow soluble powder that dissolves in drinking water and is available in 100g tubs.
Special Precautions
Use of Tylan should be based on susceptibility testing of the bacteria isolated from the animal. If this is not possible, therapy should be based on local (regional, farm level) epidemiological information about susceptibility of the target bacteria. Tylan may induce irritation for humans. Macrolides, such as tylosin, may also cause hypersensitivity (allergy) following injection, inhalation, ingestion or contact with the skin or eyes.
Target species
For use in calves, pigs, chickens and turkeys .
Indications for use, specifying the target species
For the control of Mycoplasma synoviae airsacculitis in chickens and Mycoplasma gallisepticum S6 in chickens and turkeys. In the field tylosin has also proved useful in reducing the level of infection following stress associated with live vaccination. As an aid in the control of outbreaks of necrotic enteritis in chickens caused by Clostridium perfringens. For the prevention and control of enzootic pneumonia, and scours caused by organisms (e.g. Lawsonia intracellularis) sensitive to tylosin, in pigs. For the control of pneumonia in cattle associated with mycoplasmata and Pasteurella multocida sensitive to tylosin. For information regarding swine dysentery see section
Special precautions for use.
Contraindications
Do not leave or dispose of water containing tylosin tartrate where it may be accessible to either animals not under treatment or to wildlife. Do not use in known cases of hypersensitivity to tylosin or other macrolides.
Special warnings for each target species
None
Special precautions for use
Special precautions for use in animals
Use of the product should be based on susceptibility testing of the bacteria isolated from the animal. If this is not possible, therapy should be based on local (regional, farm level) epidemiological information about susceptibility of the target bacteria. Official, national and regional antimicrobial policies should be taken into account when the product is used. A high rate of in vitro resistance has been demonstrated in European strains of Brachyspira hyodysenteriae implying that the product will not be sufficiently efficacious against swine dysentery. Use of the product deviating from the instructions given in the SPC may increase the prevalence of bacteria resistant to tylosin and may decrease the effectiveness of treatment with other macrolides, lincosamides and streptogramin B due to the potential for cross-resistance.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Tylosin may induce irritation. Macrolides, such as tylosin, may also cause hypersensitivity (allergy) following injection, inhalation, ingestion or contact with skin or eye. Hypersensitivity to tylosin may lead to cross reactions to other macrolides and vice versa. Allergic reactions to these substances may occasionally be serious and therefore direct contact should be avoided. To avoid exposure during preparation of the medicated drinking water, wear overalls, safety glasses, impervious gloves and wear either a disposable half mask respirator conforming to European Standard EN149 or a non-disposable respirator to European Standard EN140 with a filter to EN143. Wash hands after use. In the event of accidental skin contact, wash thoroughly with soap and water. In case of accidental eye contact, flush the eyes with plenty of clean, running water. Do not handle the product if you are allergic to ingredients in the product. If you develop symptoms following exposure, such as skin rash, you should seek medical advice and show the physician this warning. Swelling of the face, lips and eyes or difficulty in breathing are more serious symptoms and require urgent medical attention.
Adverse reactions (frequency and seriousness)
None known
Use during pregnancy, lactation or lay
No adverse effects to tylosin have been seen in fertility, multi-generation or teratology studies.
Interaction with other medicinal products and other forms of interaction
None known
